Evidence that the low-affinity folate-binding protein in erythrocyte hemolysate is identical to hemoglobin.
نویسندگان
چکیده
Gel filtration studies on erythrocyte hemolysate demonstrated the presence of a folate binding protein, apparently of the low-affinity type, that co-elutes with hemoglobin. Further, the folate binder eluted with a low salt concentration after DEAE-Sepharose CL-6B anion-exchange chromatography of erythrocyte hemolysate at pH 6.3. The chromatographic behavior of hemoglobin labeled with [3H]folate was so similar to that of the present binder as to suggest that the folate binder in erythrocytes is in fact hemoglobin.
منابع مشابه
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 27 7 شماره
صفحات -
تاریخ انتشار 1981